Antibacterial peptides are the
effector molecules
of innate immunity
and acts as the first line of host defense
against
pathogenic
infections . Generally they contain 15-45 amino acid residues and the
net charge is positive.Antibacterial peptides
have been identified in
various species ranging from bacteria, frogs to mammals, including
humans.Database of antibacterial
peptides (DABP) has been established
based
on an extensive literature search. Peptide informations can be searched
using
keywords such as peptide name, sequence
, structure
and activity. DABP
is a useful tool for studying the structure -function
relationship of
antibacterial peptides. The structural and sequence information of
these peptides can be retrieved from PDB
and Swiss-Prot.
Antibacterial peptides were
collected from the
literature by PubMed
search. A web link for Swiss-prot, Interpro, PIR are
created in DABP
for each peptide entry to provide more useful information's regarding
peptides. In addition, each entry also
contains peptide name, gene
name, source, sequence, length, hydrophobic ,molecular mass,net charge
,structure (such as a-
helix
or beta strand), biological activity, crucial residues for and
taxonomic classification to provide information about
evolutionary
relationships of the peptides.